Louise is one of six sisters and three brothers. She went to primary school at Stirling Station, a cattle station near Tennant Creek. She later studied at Yirara College in Alice Springs. After her studies, she returned to Stirling Station working with the Community Development Program. It was during her return to Stirling Station she began painting in 1981, taking guidance from her aunties Gloria and Kathleen Petyarre. Louise lives in Darwin with her two sisters, Jacinta and Lanita Numina, who are also well-renowned artists from Utopia.